Title: The Integrated Use of Alternative Approaches for Predicting Toxic Hazard
Authors: BARRATT Martin d.CASTELL Jose v.CHAMBERLAIN MarkCOMBES Robert d.DEARDEN John c.FENTEM Julia helenGERNER IngridGIULIANI AlessandroGRAY Tim j.b.LIVINGSTONE David j.PROVAN W. mcleanRUTTEN Fons a.j.j.l.VERHAAR HenkZBINDEN Peter
Citation: Alternatives to Laboratory Animals (ATLA) vol. 23 p. 410-429
Publication Year: 1996
JRC N°: JRC13638
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC13638
Type: Articles in Journals
Abstract: Ways in which QSARs might be used in the design, evaluation and validation of in vitro tests, and in the selection of appropriate test chemicals for validation studies, are described. Reference is made to the following: availability of high quality ddata; integration of QSAR and in vitro methods; and methodology (PBPK modelling, statistical methods), validation and selection of test chemicals.
JRC Institute:Joint Research Centre Historical Collection

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