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|Title:||The Integrated Use of Alternative Approaches for Predicting Toxic Hazard|
|Authors:||BARRATT Martin d.; CASTELL Jose v.; CHAMBERLAIN Mark; COMBES Robert d.; DEARDEN John c.; FENTEM Julia helen; GERNER Ingrid; GIULIANI Alessandro; GRAY Tim j.b.; LIVINGSTONE David j.; PROVAN W. mclean; RUTTEN Fons a.j.j.l.; VERHAAR Henk; ZBINDEN Peter|
|Citation:||Alternatives to Laboratory Animals (ATLA) vol. 23 p. 410-429|
|JRC Publication N°:||JRC13638|
|Type:||Articles in Journals|
|Abstract:||Ways in which QSARs might be used in the design, evaluation and validation of in vitro tests, and in the selection of appropriate test chemicals for validation studies, are described. Reference is made to the following: availability of high quality ddata; integration of QSAR and in vitro methods; and methodology (PBPK modelling, statistical methods), validation and selection of test chemicals.|
|JRC Institute:||Joint Research Centre Historical Collection|
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