Title: ECVAM Biostatistics Task Force 1. Recommendations for the Application of Biostatistical Methods during the Development and Validation of Alternative Toxicological Methods.
Authors: HOLZHUETTER Hermann, g.ARCHER GraemeDAMI N.SALTELLI AndreaSJOSTROM M.
Citation: Atla vol. 24 p. 511-530
Publication Year: 1996
JRC N°: JRC14397
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC14397
Type: Articles in Journals
Abstract: Assessment of the relevance and reliability of alternative toxicological methods requires the application of biostatistical methods. This report contains the recommendations of the ECVAM Task Force on Biostatistics for the appropriate use of biometrical methods and for closer collaboration between biostatisticians and experimental toxicologists in the development and validation of alternative methods. The main, objectives of these recommendations are to improve the compatibility of the results obtained from different studies, and to prevent the misinterpretation of statistical analyses. The following points are discussed: the general importance of biostatistics in the development and validation of alternative tests; optimisation of study designs; statistical characterisation and processing of toxicological data; the analysis of relationships which may exist between data obtained from various tests.
JRC Institute:Joint Research Centre Historical Collection

Files in This Item:
There are no files associated with this item.


Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.