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|Title:||Pharmacokinetics in Early Drug Research. The Report and Recommendations of ECVAM Workshop 22.|
|Authors:||LEAHY David; DUNCAN Ruth; AHR Hans; BAYLISS Martin, k.; DE BOER Bert, g.; DARVAS Ferenc; FENTEM Julia helen; FRY Jeffrey, r.; HOPKINS Robert; HOUSTON Brian, j.; KARLSSON Johan; KEDDERIS Gregory, l.; PRATTEN Margaret; SMITH Dennis, a.; STRAUGHAN Donald w.|
|Citation:||Alternatives to Laboratory Animals (ATLA) vol. 25 p. 17-31|
|JRC Publication N°:||JRC14551|
|Type:||Articles in Journals|
|Abstract:||This report of an ECVAM workshop on pharmacokinetics in early drug research: a) reviews the current methodology for providing early pharmacokinetic and related information; b) defines current best practice and identifies those problem areas where scientific and technological advances could significantly improve the efficiency of drug discovery; and c) recommends further work which should be conducted in these high priority areas, which coul lead to a more effective use of animal studies while increasing the capacity for efficient optimisation of activity in vivo.|
|JRC Institute:||Joint Research Centre Historical Collection|
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