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|Title:||Comparative Review of QSARs for Acute Toxicity Part I: QSARs for Toxicity to Aquatic Organisms Part II: QSARs for Toxicity to Terrestrial Organisms|
|Authors:||LESSIGIARSKA Iglika; WORTH ANDREW; NETZEVA TATIANA|
|Other Identifiers:||EUR 21559 EN|
|Type:||EUR - Scientific and Technical Research Reports|
|Abstract:||A large number of QSARs for acute toxicity have been developed and published. Toxicity to a wide variety of biological systems was investigated, including bacteria, algae, Daphnia, fish, fungi, plants, and mammals. The aim of this paper is to review and compare some of these QSARs. The review focuses on recently-published QSAR models (since 2000), which were developed using more traditional statistical methods (regression analysis, partial least squares analysis), rather than neural network approaches, for example. In the first part of the review QSARs for toxicity to aquatic organisms (aquatic bacteria, protozoa, algae, Hydraozoa, Daphnia, fish, and amphibians) are presented. The second part includes QSARs for toxicity to terrestrial organisms – bacterial species, fungi, worms, insects, plants, mammalian cells, and mammals, including humans.|
|JRC Institute:||Institute for Health and Consumer Protection|
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