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|Title:||Immobilization of RGD Peptides on Stable Plasma-Deposited Acrylic Acid Coatings for Biomedical Devices|
|Authors:||LOPEZ L.c.; GRISTINA R.; CECCONE GIACOMO; ROSSI FRANCOIS; FAVIA P.; D'AGOSTINO R.|
|Citation:||SURFACE & COATINGS TECHNOLOGY vol. 200 no. 1-4 p. 1000-1004|
|JRC Publication N°:||JRC31902|
|Type:||Articles in Journals|
|Abstract:||Thin coatings were deposited in high fragmentation regimes from RF (13.56 MHz) glow discharges fed with acrylic acid vapours. These coatings were characterized by a low surface density of COOH groups and resulted homogeneous and very stable in water. PET coated samples were used for the covalent immobilization of RGD peptide via a bis amine spacer arm, using COOH surface functionalities as anchor groups. Substrates from the different steps of RGD immobilization were used for cell adhesion assays with 3T3 fibroblasts.|
|JRC Institute:||Institute for Health and Consumer Protection|
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