Title: Certification of the Amount-of-Substance Fraction of HbA0 versus the Sum of all Hb Isoforms forming the glycated or non-glycated Hexapeptide of the -chain in haemoglobin isolated from whole Blood, IRMM/IFCC-467
Publisher: OPOCE
Publication Year: 2007
JRC N°: JRC37621
ISBN: 978-92-79-06043-4
ISSN: 1018-5593
Other Identifiers: EUR 22788 EN
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC37621
Type: EUR - Scientific and Technical Research Reports
Abstract: This report describes the preparation, homogeneity, stability and certification studies of HbA0 (IRMM/IFCC-467) from human blood. HbA0 is defined as the non-glycated haemoglobin. The amount-of-substance fraction of HbA0 in IRMM/IFCC-467 is > 976 mmol/mol (expressed as mmol HbA0 per mol HbA1c plus HbA0). HbA1c is defined as the beta-N-(1-deoxyfructos-1-yl) haemoglobin. The indended use of this certified reference material is the calibration of the IFCC reference measurement procedure and other analogous methods based on the quantification of the N-terminal hexapeptide including the stable glycation.
JRC Directorate:Health, Consumers and Reference Materials

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