Title: Certification of Reference Materials for Detection of the Human Prothrombin Gene G20210A Sequence Variant
Authors: GANCBERG DAVIDCORBISIER PHILIPPEMEEUS NELEMANNHALTER ChristineSCHIMMEL HEINZMARKI-ZAY J.
Citation: CLINICAL CHEMISTRY AND LABORATORY MEDICINE vol. 46 no. 4 p. 463-469
Publisher: WALTER DE GRUYTER & CO
Publication Year: 2008
JRC N°: JRC41802
ISSN: 1434-6621
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC41802
DOI: 10.1515/CCLM.2008.093
Type: Articles in Journals
Abstract: There is a need for reference materials in the field of genetic testing for verification of tests results obtained in patients and probands. New types of certified reference materials (CRMs) for genetic testing of the human prothrombin gene G20210A mutation are available. Homogeneity, stability and fitness for the purpose of the plasmids could be demonstrated and no evidence was found that they would not work with other methods as long as these are targeting the whole or parts of the prothrombin gene fragment inserted into the plasmids. The described CRMs support the efforts of the international community in development, validation and harmonisation of tests for molecular genetic testing
JRC Institute:Institute for Reference Materials and Measurements

Files in This Item:
There are no files associated with this item.


Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.