Title: An International Comparability Study to Determine the Sources of Uncertainty Associated with a Non-competitive Sandwich Fluorescent ELISA
Authors: NOBLE James E.WANG LiliCERASOLI EleonoraKNIGHT Alex E.PORTER Robert A.GRAY ElaineHOWE ChrisCORBISIER PHILIPPEWANG J.WU LiqingALTIERI IlariaPATRIARCA MarinaHOFFMAN AngelikaRESCH-GENGER UteEBERT BerndVOIGT JanSHIGERI YasushiVONSKY MaximKONOPELKO LeonidGAIGALAS Adolfas K.BAILEY Marc J. A.HANNES E.
Citation: CLINICAL CHEMISTRY AND LABORATORY MEDICINE vol. 46 no. 7 p. 1033-1045
Publisher: WALTER DE GRUYTER & CO
Publication Year: 2008
JRC Publication N°: JRC41959
ISSN: 1434-6621
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC41959
DOI: 10.1515/CCLM.2008/182
Type: Articles in Journals
Abstract: Immunoassays allow the specific detection of biological molecules in complex samples at physiologically relevant concentrations. However, there are concerns over the comparability of such techniques when the same assay is performed by different operators or laboratories. an international intercomparison study was performed to assess the uncertainty involved in the estimation of a protein cytokine concentration using a fluorescent ELISA.
JRC Institute:Institute for Reference Materials and Measurements

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