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|Title:||Use of Nanopatterned Surfaces To Enhance Immunoreaction Efficiency|
|Authors:||VALSESIA ANDREA; COLPO PASCAL; MANNELLI ILARIA; MORNET Stephane; BRETAGNOL FREDERIC; CECCONE GIACOMO; ROSSI FRANCOIS|
|Citation:||ANALYTICAL CHEMISTRY vol. 80 no. 5 p. 1418-1424|
|Publisher:||AMER CHEMICAL SOC|
|Type:||Articles in periodicals and books|
|Abstract:||In this work, we compare the immunoreaction efficiency between uniformly functionalized surface and chemically nanopatterned surfaces when applied as platforms for antigen/antibody interactions with and without the use of protein A as orienting protein. On the anopatterned platform, the immunoreaction efficiency is higher than all the other cases with no protein A pretreatment of the surface, providing evidence of the capability of the adhesive/antiadhesive nanopatterned surface to immobilize the molecules in a reactive state, increasing their possibility to form complexes.|
|JRC Institute:||Institute for Health and Consumer Protection|
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