Title: The ACuteTox Project: Optimization and Prevalidation of an In Vitro Test Strategy for Predicting Human Toxicity
Authors: HARTUNG Thomas
Citation: Report on the ICCVAM-NICEATM/ECVAM/JaCVAM Scientific Workshop on Acute Chemical Safety Testing: Advancing In Vitro Approaches and Humane Endpoints for Systemic Toxicity Evaluations p. 5.6-5.9
Publisher: National Institutes of Health
Publication Year: 2009
JRC Publication N°: JRC46512
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC46512
Type: Contributions to Conferences
Abstract: This presentation provided a review of the ACuteTox approach and the models proposed for replacing in vivo acute oral toxicity testing with an in vitro test battery strategy examining parameters such as ADME and organ specificity (nervous system, kidney and liver) to predict human oral toxicity
JRC Institute:Institute for the Protection and Security of the Citizen

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