Title: Radiofungicidal Effects of External Gamma Radiation and Antibody-Targeted Beta and Alpha Radiation on Cryptococcus neoformans
Authors: BRYAN R. A.MORGENSTERN AlfredBRUCHERTSEIFER FrankCASADEVALL A.DADACHOVA E.
Citation: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY vol. 52 no. 6 p. 2232-2235
Publisher: AMER SOC MICROBIOLOGY
Publication Year: 2008
JRC Publication N°: JRC48528
ISSN: 0066-4804
URI: http://aac.asm.org/
http://publications.jrc.ec.europa.eu/repository/handle/JRC48528
DOI: 10.1128/AAC.01245-07
Type: Articles in Journals
Abstract: We evaluated the clonogenic survival, membrane permeability, metabolic activity (XTT reduction), and apoptosis (FLICA binding) of Cryptococcus neoformans cells subjected to gamma rays from an external source, and beta and alpha particles delivered to fungal cells by capsule-specific antibody. We found that gamma, beta, and alpha radiation affected cells through different pathways.
JRC Institute:Institute for Transuranium Elements

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