Title: Protein Nanopatterns for Improved Immunodetection Sensitivity
Authors: VALSESIA AndreaMANNELLI IlariaCOLPO PascalBRETAGNOL FredericROSSI Francois
Citation: ANALYTICAL CHEMISTRY vol. 80 no. 19 p. 7336-7340
Publisher: AMER CHEMICAL SOC
Publication Year: 2008
JRC N°: JRC48967
ISSN: 0003-2700
URI: http://pubs.acs.org/doi/abs/10.1021/ac801021z
http://publications.jrc.ec.europa.eu/repository/handle/JRC48967
DOI: 10.1021/ac801021z
Type: Articles in Journals
Abstract: In this work, we clearly demonstrate the capability of protein nanopatterns of improving the quality factors of immunosensing devices, such as lowering of the limit of detection and increase of sensitivity. This beneficial effect is obtained by the formation on the sensor's surface of bioadhesive domains of nanometric dimensions in a nonadhesive matrix by means of colloidal lithography.
JRC Institute:Institute for Health and Consumer Protection

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