Title: Nanocrystalline Diamond/Amorphous Carbon Composite Coatings for Biomedical Applications
Authors: POPOV CyrilBLIZNAKOV S.BOYCHEVA S.MILINOVIK N.APOSTOLOVA M. D.ANSPACH N.HAMMANN C.NELLEN W.REITHMAIER J. P.KULISCH Wilhelm
Citation: DIAMOND AND RELATED MATERIALS vol. 17 no. 4-5 p. 882-887
Publisher: ELSEVIER SCIENCE SA
Publication Year: 2008
JRC Publication N°: JRC49879
ISSN: 0925-9635
URI: http://dx.doi.org/10.1016/j.diamond.2007.10.017
http://publications.jrc.ec.europa.eu/repository/handle/JRC49879
DOI: 10.1016/j.diamond.2007.10.017
Type: Articles in Journals
Abstract: Nanocrystalline diamond/amorphous carbon (NCD/a-C) composite films have been prepared by microwave plasma chemical vapor deposition (MWCVD) from methane/nitrogen mixtures and investigated with respect of their bioproperties. By means of atomic force microscopy (AFM) it was shown that RNA molecules can be attached to the NCD/a-C surface, which has been treated in hydrogen plasma and biochemically modified prior to the attachment. Further experiments addressed the influence of the morphology of the films on the viability and proliferation of endothelial cells. The results from scanning electron microscopy (SEM) and fluorescent microscopy revealed that homogeneous and uniform NCD/a-C films did not affect the cell shape and cytoskeleton, in contrast to films composed of individual nodules.
JRC Institute:Institute for Health and Consumer Protection

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