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|Title:||Production of cerium radioisotopes for nanotechnology studies: experimental measurements of the excitation functions natCe(d,x)139g/141/143Ce and 142Pr|
|Authors:||ABBAS Kamel; SIMONELLI Federica; CYDZIK Izabela; HOLZWARTH Uwe; GIBSON Peter|
|Citation:||JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS vol. 52 no. S1 p. S231|
|Publisher:||JOHN WILEY & SONS LTD|
|Type:||Articles in periodicals and books|
|Abstract:||In recent years, the production and utilisation of nanoparticles (particles with a size range of about 1 to a few hundred nm) have dramatically increased as new information about these particles and their potential applications are gained. In this respect, cerium may play an important role in the field of nanoscience as potential uses of Ce oxide nanoparticles are under evaluation in different fields, ranging from fuel additives, to UV sunblock, and to various medical applications. As the use of nanoparticles has increased, so also has concern about their possible detrimental effects on health or the environment, and considerable effort nowadays is devoted to their safety studies. In this respect, radiolabelling of nanoparticles can be a very useful tool for determination of nanoparticle fate, biodistribution, in vitro cellular uptake, etc. In this work, we focus on the study of the production of Ce radioisotopes and more precisely on the determination of the thin-target excitation functions for Ce radioisotope productions by deuteron-induced nuclear reactions in natural Ce, as no such data are available. Suitably radio-labelled Ce nanoparticles can be traced at different stages of their application thanks to the sensitivity of radiation measurements.|
|JRC Institute:||Institute for Health and Consumer Protection|
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