Title: New approaches in GMO detection
Authors: QUERCI MaddalenaVAN DEN BULCKE MARCZEL JanaVAN DEN EEDE GuyBROLL Hermann
Citation: ANALYTICAL AND BIOANALYTICAL CHEMISTRY vol. 396 no. 6 p. 1991-2002
Publisher: SPRINGER HEIDELBERG
Publication Year: 2010
JRC N°: JRC53461
ISSN: 1618-2642
URI: http://www.springerlink.com/content/88211783g3035366/
http://publications.jrc.ec.europa.eu/repository/handle/JRC53461
DOI: 10.1007/s00216-009-3237-3
Type: Articles in Journals
Abstract: The steady rate of development and diffusion of GM plants and their increasing diversification in characteristics, genes and genetic control elements poses a challenge in GMO analysis. It is expected that in the near future the picture will be even more complex. Traditional approaches, mostly based on the sequential detection of one target at a time, or on a limited multiplexing, allowing only few targets to be analysed at once, do no longer meet the testing requirements. Along with the development of new analytical technologies, new approaches towards global GMO analysis have been developed that rely on 1) a smart and accurate strategy for target selection, 2) the use of high throughput systems or platforms for the detection of multiple targets and 3) on algorithms that allow the conversion of analytical results into an indication of the presence of individual GMO(s) potentially present in an unknown sample. This paper addresses the critical aspects listed above taking examples from the most recently developed strategies and tools.
JRC Institute:Institute for Health and Consumer Protection

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