Title: Knowledge-technology-based discovery of unauthorized genetically modified organisms
Authors: RUTTINK TomMORISSET DanyVAN DROOGENBROECK BartLAVRAC NadaVAN DEN EEDE GuyZEL JanaDE LOOSE Marc
Citation: ANALYTICAL AND BIOANALYTICAL CHEMISTRY vol. 396 no. 6 p. 1951-1959
Publisher: SPRINGER HEIDELBERG
Publication Year: 2010
JRC Publication N°: JRC54843
ISSN: 1618-2642
URI: http://www.springerlink.com/content/yt18331041031545/
http://publications.jrc.ec.europa.eu/repository/handle/JRC54843
DOI: 10.1007/s00216-009-3218-6
Type: Articles in Journals
Abstract: Various legislations worldwide provide a framework for the authorization of genetically modified organisms (GMOs) and products derived therefrom [1]. Despite these regulations, novel GMOs occasionally enter the market without authorization [2¿22] (Table 1) and are referred to as unauthorized GMOs (UGMs). The presence of UGMs in food and feed raises safety and labeling concerns, and challenges international trade [23, 24]. Recently reported UGM incidents have created an urgent need to harmonize regulations at a global level, and call for appropriate strategies to discover UGMs. However, some novel UGMs are intrinsically difficult to detect using current analytical strategies for reasons outlined herein. We therefore propose a paradigm shift in the way UGMs can be discovered: a documentationbased screening for products that potentially contain UGMs using knowledge technologies, followed by analytical confirmation. Here, we will describe the main concepts of the novel approach, illustrate it with a case study, and outline benefits, limitations, and complementarities compared with the current analytical detection strategy.
JRC Institute:Institute for Health and Consumer Protection

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