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|Title:||Medical radioisotopes activation in the JRC cyclotron-driven INBARCA neutron activator|
|Authors:||MACIOCCO L.; BUONO S.; ABBAS Kamel; COTOGNO Giulio; GIBSON Peter; SIMONELLI Federica; TAGZIRIA Hamid; BURGIO N.; SANTAGATA A; MERCURIO GIOVANNI; TALAB J.; BILLOTEY C.|
|Citation:||EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING vol. 36 (Supplement 2) p. S401|
|Type:||Articles in periodicals and books|
|Abstract:||A compact, accelerator driven, neutron activator based on a modified version of the Adiabatic Resonance Crossing (ARC) concept has been developed, with the aim of efficiently utilising ion-beam generated neutrons for the production of radioactive nanoparticles for brachytherapy. The facility has been tested under various experimental configurations, and the activation yields of different materials, measured with ¿-spectrometry techniques, have been compared with those of our Monte Carlo (MCNPX, FLUKA) simulations. In particular two version of the activator were tested: a lead-graphite and an all-graphite configuration. Experimental results, in agreement with Monte Carlo calculations, showed that higher activation rates (factor 1.7) are obtained for the isotopes of interest (166Ho (T1/2=26.8h), 186Re(T1/2=3.7d) and 188Re (T1/2=0.71d)) as a result of the improved neutron moderation/confinement effects of the all-graphite configuration.|
|JRC Institute:||Institute for Health and Consumer Protection|
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