Title: Methylene Diphenyl Diisocyanate
Authors: DEBACKER LindaJOAQUIM-JUSTO C.NEMERY B.THOMÉ J.p.VANHOOREN H.VAN MALDEREN Karen
Editors: ASCHBERGER KARIN
MUNN SHARON
OLSSON Heidi
PAKALIN Sazan
PAYA PEREZ Ana
PELLEGRINI Grazia
VEGRO Stefania
Publisher: Publications Office of the Europen Union
Publication Year: 2010
JRC N°: JRC56623
ISBN: 978-92-79-14996-2
ISSN: 1018-5593
Other Identifiers: EUR 24244 EN
OPOCE LB-NA-24244-EN-N
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC56623
DOI: 10.2788/60947
Type: EUR - Scientific and Technical Research Reports
Abstract: The report provides the comprehensive risk assessment of the substance Methylenediphenyl diisocyanate (MDI). It has been prepared by Belgium in the frame of Council Regulation (EEC) No. 793/93 on the evaluation and control of the risks of existing substances, following the principles for assessment of the risks to humans and the environment, laid down in Commission Regulation (EC) No. 1488/94. Part I - Environment This part of the evaluation considers the emissions and the resulting exposure to the environment in all life cycle steps. Following the exposure assessment, the environmental risk characterisation for each protection goal in the aquatic, terrestrial and atmospheric compartment has been determined. The environmental risk assessment concludes that there is no concern. Part II ¿ Human Health This part of the evaluation considers the emissions and the resulting exposure to human populations in all life cycle steps. The scenarios for occupational exposure, consumer exposure and humans exposed via the environment have been examined and the possible risks have been identified. The human health risk assessment concludes that there is concern for workers and consumers with regard to irritation of skin, eye and respiratory tract, skin sensitisation and lung effects induced by repeated inhalation exposure. There is a need for further information and for testing (on hold) on the toxicity for fertility for workers and consumers. For humans exposed via the environment and for human health (physico-chemical properties) there is no concern. The conclusions of this report will lead to risk reduction measures to be proposed by the Commission¿s committee on risk reduction strategies set up in support of Council Regulation (EEC) N. 793/93.
JRC Institute:Institute for Health and Consumer Protection

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