Title: Preparation, Modification and Cellular Evaluation of PEG-PEGd Supports With Titania Nanoparticle Loads
Authors: SÁNCHEZ VAQUERO VanessaMUÑOZ NOVAL AlvaroTEJERA NuriaPEREZ ROLDAN MARIAVALSESIA AndreaCECCONE GiacomoGARCÍA RUIZ Josefa PredestinaciónMANSO SILVAN MiguelROSSI Francois
Citation: SURFACE AND INTERFACE ANALYSIS vol. 42 no. 6-7 p. 481-485
Publisher: JOHN WILEY & SONS LTD
Publication Year: 2010
JRC N°: JRC57551
ISSN: 0142-2421
URI: www.interscience.wiley.com
http://publications.jrc.ec.europa.eu/repository/handle/JRC57551
DOI: 10.1002/sia.3287
Type: Articles in Journals
Abstract: Polyethylene-glycol (PEG) films with PEG-diacrylate (PEGd) have been prepared including a Ti alkoxyde that turns the film into a nano-hybrid with potential interest for the production of controlled bioadhesive surfaces. Precursor sols were cast onto Si (100) surfaces producing conformed films. Modification of such surfaces was performed by exposing surfaces to UV light (365 nm) at different exposure times. The surface of the hybrid films was characterized by using atomic force microscopy and X-ray photoelectron spectroscopy. It is concluded that the UV exposure induces a densification of the film and an in-film coalescence of the titania nanoparticles. This had a direct effect in the wettability of the films as determined by water contact angle measurements. Both, as cast and UV modified surfaces were proved to be biocompatible as deduced from nuclear immunocytochemistry proliferation assays.
JRC Institute:Institute for Health and Consumer Protection

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