Please use this identifier to cite or link to this item:
|Title:||An external cyclotron target system for nanoparticle sample activation|
|Authors:||ABBAS Kamel; GIBSON Peter; HORSTMANN Wijbe; HOLZWARTH Uwe; ARROJA Fernando; SIMONELLI Federica; KOZEMPEL JAN; BULGHERONI ANTONIO; CYDZIK Izabela|
|Citation:||CHEMICKE LISTY vol. 104 no. 14 (Special Issue) p. s203|
|Type:||Contributions to Conferences|
|Abstract:||The need for toxicity assessment of industrially relevant nanoparticle materials implies that in vitro and in vivo biokinetics studies are required. Radiolabelled nanoparticles are an excellent candidate for such biodistribution measurements and are also of high interest for particle tracing and fate studies in other areas. We describe here an external target system for direct activation of dry nanoparticle samples, with He or water cooling, which is attached to an external beamline of the JRC Scanditronix MC-40 cyclotron at Ispra, Italy. A specially designed capsule is used to hold several tens of mg of nanoparticle powder material to be irradiated. The target system design and cooling system is described, and considerations regarding energy deposition, yield, heat transfer, radiation damage and radiotracer recoil are discussed.|
|JRC Institute:||Institute for Health and Consumer Protection|
Files in This Item:
There are no files associated with this item.
Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.