Title: First Certified Reference Material for Cystatin C in Human Serum ERM-DA471/IFCC
Authors: GRUBB AndersBLIRUP-JENSEN SorenLINDSTROM VeronicaSCHMIDT CamillaALTHAUS HaraldZEGERS Ingrid
Citation: CLINICAL CHEMISTRY AND LABORATORY MEDICINE vol. 48 no. 11 p. 1619-1621
Publisher: WALTER DE GRUYTER & CO
Publication Year: 2010
JRC Publication N°: JRC60500
ISSN: 1434-6621
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC60500
DOI: 10.1515/CCLM.2010.318
Type: Articles in Journals
Abstract: The IFCC Working Group for standardisation of Cystatin C (WG-SCC) in collaboration with the Institute for Reference Materials and Measurements (IRMM) announces the availability of the new certified reference material ERM-DA471/IFCC. The material was characterised using a pure protein primary reference preparation (PRP) as calibrant. The PRP was prepared from recombinant cystatin C and its concentration determined by dry mass determination. The characterisation of ERM-DA471/IFCC was performed by particle enhanced immune-nephelometry, particle enhanced immuno-turbidimetry, and enzyme amplified single radial ummuno-diffusion. The certified cystatin C mass concentration in ERM-DA471/IFCC is 5.48 mg/L, the expanded uncertainty (k= 2) being 0.15 mg/L
JRC Institute:Institute for Reference Materials and Measurements

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