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|Title:||First Certified Reference Material for Cystatin C in Human Serum ERM-DA471/IFCC|
|Authors:||GRUBB Anders; BLIRUP-JENSEN Soren; LINDSTROM Veronica; SCHMIDT Camilla; ALTHAUS Harald; ZEGERS Ingrid|
|Citation:||CLINICAL CHEMISTRY AND LABORATORY MEDICINE vol. 48 no. 11 p. 1619-1621|
|Publisher:||WALTER DE GRUYTER & CO|
|Type:||Articles in periodicals and books|
|Abstract:||The IFCC Working Group for standardisation of Cystatin C (WG-SCC) in collaboration with the Institute for Reference Materials and Measurements (IRMM) announces the availability of the new certified reference material ERM-DA471/IFCC. The material was characterised using a pure protein primary reference preparation (PRP) as calibrant. The PRP was prepared from recombinant cystatin C and its concentration determined by dry mass determination. The characterisation of ERM-DA471/IFCC was performed by particle enhanced immune-nephelometry, particle enhanced immuno-turbidimetry, and enzyme amplified single radial ummuno-diffusion. The certified cystatin C mass concentration in ERM-DA471/IFCC is 5.48 mg/L, the expanded uncertainty (k= 2) being 0.15 mg/L|
|JRC Institute:||Institute for Reference Materials and Measurements|
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