Title: Assessment of Dioxin-Like Activity in Ambient Air Particulate Matter Using Recombinant Yeast Assays
Authors: OLIVARES AlbaVAN DROOGE BarendPEREZ BALLESTA PascualGRIMALT Joan O.PIÑA Benjamin
Citation: ATMOSPHERIC ENVIRONMENT vol. 45 no. 1 p. 271-274
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Publication Year: 2011
JRC N°: JRC60687
ISSN: 1352-2310
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC60687
DOI: 10.1016/j.atmosenv.2010.09.039
Type: Articles in Journals
Abstract: Ectopic activation of the aryl hydrocarbon receptor (AhR), also known as dioxin-like activity, is a major component of the toxicity associated with polycyclic aromatic hydrocarbons (PAH). Filtration of ambient air particulate matter through PM10 filters followed by chemical determination of PAH concentrations and a yeast-based bioassay (RYA) were combined to evaluate and characterize dioxin-like activity in ambient air. Samples were collected in a semirural area of Northern Italy between September 2008 and February 2009. Total PAH contents ranged between 0.3 ng/m3 and 34 ng/m3 28 and were in correlation with seasonal variations of meteorological conditions and combustion processes. Dioxin-like activity values in air samples showed an excellent correlation (0.71 < R2 31 < 0.86) with the observed PAH concentrations and the predicted toxicity equivalents for PAH. This RYA bioassay reported in the present study provides a simple and low-cost routine control for toxic PAH emissions, even at background air concentration levels.
JRC Institute:Institute for Energy and Transport

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