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|Title:||Assessment of Dioxin-Like Activity in Ambient Air Particulate Matter Using Recombinant Yeast Assays|
|Authors:||OLIVARES Alba; VAN DROOGE Barend; PEREZ BALLESTA Pascual; GRIMALT Joan O.; PIÑA Benjamin|
|Citation:||ATMOSPHERIC ENVIRONMENT vol. 45 no. 1 p. 271-274|
|Publisher:||PERGAMON-ELSEVIER SCIENCE LTD|
|Type:||Articles in periodicals and books|
|Abstract:||Ectopic activation of the aryl hydrocarbon receptor (AhR), also known as dioxin-like activity, is a major component of the toxicity associated with polycyclic aromatic hydrocarbons (PAH). Filtration of ambient air particulate matter through PM10 filters followed by chemical determination of PAH concentrations and a yeast-based bioassay (RYA) were combined to evaluate and characterize dioxin-like activity in ambient air. Samples were collected in a semirural area of Northern Italy between September 2008 and February 2009. Total PAH contents ranged between 0.3 ng/m3 and 34 ng/m3 28 and were in correlation with seasonal variations of meteorological conditions and combustion processes. Dioxin-like activity values in air samples showed an excellent correlation (0.71 < R2 31 < 0.86) with the observed PAH concentrations and the predicted toxicity equivalents for PAH. This RYA bioassay reported in the present study provides a simple and low-cost routine control for toxic PAH emissions, even at background air concentration levels.|
|JRC Institute:||Institute for Energy and Transport|
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