Title: Targeted alpha therapy with 213Bi
Authors: MORGENSTERN AlfredBRUCHERTSEIFER FrankAPOSTOLIDIS Christos
Citation: Current Radiopharmaceuticals vol. 4 no. 4 p. 295 - 305
Publisher: Bentham Science Publishers Ltd.
Publication Year: 2011
JRC N°: JRC64087
ISSN: 1874-4710
URI: http://www.benthamdirect.org/pages/content.php?CRP/2011/00000004/00000004/0003CRP.SGM
http://publications.jrc.ec.europa.eu/repository/handle/JRC64087
DOI: 10.2174/1874471011104040295
Type: Articles in Journals
Abstract: The potential of targeted therapy with the alpha emitter 213Bi has been successfully demonstrated in a large number of preclinical studies and several clinical trials have provided evidence for its feasibility, safety and therapeutic efficacy. This review describes methods for the production of 225Ac and 225Ac/213Bi radionuclide generators, gives an overview of selected preclinical studies and summarizes the current clinical experience with 213Bi.
JRC Institute:Institute for Transuranium Elements

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