Title: On the use of radioisotopes to study the possible synthesis by magnetron sputtering of bimetallic nanoparticles
Authors: BOUCHAT ValerieMOREAU NVALEMBOIS BABBAS KamelFERON OGALLEZ B.HOLZWARTH UweMASEREEL BMICHIELS CSIMONELLI FedericaVANDER BORGHT TLUCAS S
Citation: SURFACE & COATINGS TECHNOLOGY vol. 205 no. 21-22 p. 4934–4940
Publisher: ELSEVIER SCIENCE SA
Publication Year: 2011
JRC N°: JRC65808
ISSN: 0257-8972
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC65808
DOI: 10.1016/j.surfcoat.2011.04.077
Type: Articles in Journals
Abstract: An approach using physical vapor deposition technology to produce nanoparticles (NPs) containing radioactive atoms and the methodology to transfer them in pure water is investigated. NPs are synthesized by magnetron sputtering at high pressure and radioactive atoms are loaded on magnetron cathodes prior to sputtering. The technique was tested for gold cathode loaded with 57/58Co and 195/196Au. Linked to biological vector molecules, the nanoparticles can be used to enhance diagnostic sensitivity in medical imaging or to treat cancer. Sizes and morphologies of the NPs were analyzed by electron microscopy, UV-Visible spectroscopy and atomic absorption spectroscopy. Results show well dispersed NPs with sizes varying between 5 and 10 nm. Activities of these NPs were measured with a CAPINTEC well counter and a High Purity Germanium detector system. Centrifugation analyses also demonstrate that the choice of the activated metal which can be alloyed with NPs plays an important role in the synthesis. This was confirmed by the Au–Co phase diagram that shows that cobalt cannot be included efficiently in the gold NPs conversely to gold.
JRC Institute:Institute for Health and Consumer Protection

Files in This Item:
There are no files associated with this item.


Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.