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|Title:||Point: Put simply, standardization of Cardiac Troponin I is complicated|
|Authors:||CHRISTENSON Robert; BUNK David; SCHIMMEL Heinz; TATE Jilian|
|Citation:||CLINICAL CHEMISTRY vol. 58 no. 1 p. 165-168|
|Publisher:||AMER ASSOC CLINICAL CHEMISTRY|
|JRC Publication N°:||JRC66171|
|Type:||Articles in Journals|
|Abstract:||The manuscript presents the point of view in favour of standardisation in a point-counterpoint article series in Clinical Chemistry. The article stresses the importance of reference measurement procedures and defining appropriately the analytical target taking the particular biochemistry of troponin I, a very important hart infarction marker, into consideration. The biochemical challenges in troponin I standardisation and the concept followed by the IFCC working group aiming at the establishment of a reference system are described. The conclusion is drawn that standardisation of troponin I is complicated but possible and worth the effort seen the positive impact of a successful standardisation on clinical decision making and patient care.|
|JRC Institute:||Institute for Reference Materials and Measurements|
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