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|Title:||How to Reliably Test for GMOs|
|Authors:||ZEL Jana; MILAVEC Mojca; MORISSET Dany; PLAN DAMIEN; VAN DEN EEDE Guy; GRUDEN Kristina|
|JRC Publication N°:||JRC67438|
|Abstract:||Accurate and reliable testing is necessary to support the requirements of legislation on genetically modified organisms (GMO) defining their traceability and labelling. In this book, an overview of all key topics relevant to GMO testing is presented, including practical experience and generally accepted laboratory practices. GMO legislation, sources of information on GMOs, organization of the testing laboratory focusing on aspects of quality system and methods for testing are described. Additionally, precise information on qualitative and quantitative real-time PCR detection with special attention to critical points and important precautionary measures to assure reliable and accurate analyses are given. Special attention was given also to metrological topics, such as validation and verification of methods and measurement uncertainty. The approaches for GMO detection, which are precisely described in the present document, are also relevant for other areas where detection and identification rely on nucleic acid-based methods. Numerous diverse GMOs are coming onto the market including GMOs produced by new technologies, which are challenging established systems of analysis, therefore new developments in detection technologies and bioinformatics solutions are presented.|
|JRC Institute:||Institute for Health and Consumer Protection|
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