Title: The Vaccines Consistency Approach Project: an EPAA Initiative
Authors: DE MATTIA FabrizioHENDRIKSEN CoenraadBUCHHEIT Karl-HeinzCHAPSAL Jean-MichelHALDER MariaLAMBRIGTS DenisREDHEAD KeithROMMEL EddySCHARTON-KERSTEN TanyaSESARDIC TheaVIVANI LauraRAGAN Ian
Citation: PHARMEUROPA BIO & SCIENTIFIC NOTES p. 30-56
Publisher: EUROPEAN DIRECTORATE FOR THE QUALITY OF MEDICINES
Publication Year: 2015
JRC N°: JRC72058
ISSN: 2075-2164
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC72058
Type: Articles in periodicals and books
Abstract: The consistency approach for release testing of established vaccines promotes the use of in vitro, analytical, non-animal based systems allowing the monitoring of quality parameters during the whole production process. By using highly sensitive non-animal methods, the consistency approach has the potential to improve the quality of testing and to foster the 3Rs (replacement, refinement and reduction of animal use) for quality control of established vaccines. This concept offers an alternative to the current quality control strategy which often requires large numbers of laboratory animals. In order to facilitate the introduction of the consistency approach for established human and veterinary vaccine quality control, the European Partnership for Alternatives to Animal Testing (EPAA) initiated a project, the “Vaccines Consistency Approach Project”, aiming at developing and validating the consistency approach with stakeholders from academia, regulators, OMCLs, EDQM, European Commission and industry. This report summarises progress since the project’s inception.
JRC Directorate:Institute for Health and Consumer Protection Historical Collection

Files in This Item:
There are no files associated with this item.


Items in repository are protected by copyright, with all rights reserved, unless otherwise indicated.