This report provides background material for the identification and elicitation of scenarios relevant for the futures of the agriculture-energy-ecosystems-water nexus in the Danube region. We present a summary of the regional climate scenarios available as input for water resources simulations, and the consequent long term average water balance figures estimated using a Budyko framework. Then we introduce the LUISA model for the simulation of land use-related variables in the region. Finally, we include a contribution by a water expert from the Danube region, presenting an initial reasoning on important elements to be addressed in scenario simulations. This report is intended as a reader for water professionals, stakeholders and decision makers in the Danube region, in order to stimulate the foresight of scenarios worth being simulated with JRC models, so to further our understanding of the water-energy-agriculture-ecosystems nexus and its management in the mid- and long-term.