@article{JRC17165, address = {}, year = {1999}, author = {Draper D and Pereira A and Prado P and Saltelli A and Cheal R and Eguilior S and Mendes B and Tarantola S}, abstract = {A two-step approach to sensitivity analysis of model output in large computational models is proposed. A preliminary screening exercise is suggested in order to identify the subset of the most potentially explanatory factors. Afterwards, a quantitative method is recommended on the subset of pre-selected inputs. The advantage of the proposed procedure is that, very often, among a large number of input factors, only a few have a significant effect on the model output. The approach provides quantitative sensitivity measures while controlling the computational cost of the experiment. The procedure has been tested on a recent version of a chemical kinetics model of the tropospheric oxidation pathways of dimethylsulphide, including 68 uncertain factors. }, title = {Scenario and Parametric Uncertainty in GESAMAC. A Methodological Study in Nuclear Waste Disposal Risk Assessment.}, type = {}, url = {}, volume = {117}, number = {}, journal = {Computer Physics Communications}, pages = {142-155}, issn = {}, publisher = {}, doi = {} }