@article{JRC37022,
	address = {AMSTERDAM (NETHERLANDS)},
	year = {2007},
	author = {Wasik A and Mccourt J and Buchgraber M},
	abstract = {A high performance liquid chromatographic method with evaporative light scattering detection (HPLC-ELSD) has been developed for the simultaneous determination of multiple sweeteners, i.e., acesulfame-K, alitame, aspartame, cyclamic acid, dulcin, neotame, neohesperidine dihydrochalcone, saccharin and sucralose in carbonated and non-carbonated soft drinks, canned or bottled fruits and yoghurt. The procedure involves an extraction of the nine sweeteners with a buffer solution, sample clean-up using solid-phase extraction cartridges followed by an HPLC-ELSD analysis. The trueness of the method was satisfactory with recoveries ranging from 93 to 109 % for concentration levels around the maximum usable dosages for authorised sweeteners and from 100 to 112 % for unauthorised compounds at concentration levels close to the limit of quantification (LOQs). Precision measures showed mean repeatability values of <4 % (expressed as relative standard deviation) for highly concentrated samples and <5 % at concentration levels close to the LOQs. Intermediate precision was in most cases <8 %. The limits of detection (LODs) were below 15 µg g-1 and the LOQs below 30 µg g-1 in all three matrices. Only dulcin showed slightly higher values, i.e., LODs around 30 µg g-1 and LOQs around 50 µg g-1.
		
		
		
		
		
		
		},
	title = {Simultaneous Determination of Nine Intense Sweeteners in Foodstuffs by High Performance Liquid Chromatography and Evaporative Light Scattering Detection - Development and  Single-Laboratory Validation},
	type = {},
	url = {},
	volume = {1157},
	number = {1-2},
	journal = {JOURNAL OF CHROMATOGRAPHY A},
	pages = {187-196},
	issn = {0021-9673},
	publisher = {ELSEVIER SCIENCE BV},
	doi =