@techreport{JRC79446,
	number = {LB-NA-25816-EN-C (print), LB-NA-25816-EN-N (online)},
	address = {Luxembourg (Luxembourg)},
	issn = {1018-5593 (print),1831-9424 (online)},
	year = {2013},
	author = {Casati S and Worth A and Amcoff SP and Whelan M},
	isbn = {978-92-79-28646-9 (print),978-92-79-28645-2 (pdf)},
	publisher = {Publications Office of the European Union},
	abstract = {In the absence of validated and regulatory accepted alternative methods, the assessment of the skin sensitisation potential of chemicals still relies on animal testing. Progress in the development of alternative methods has been prompted by the increasing knowledge on the key mechanisms of the skin sensitisation pathway, as recently documented in the OECD Adverse Outcome Pathway for skin sensitisation. Based on an analysis of the regulatory requirements for this endpoint within relevant pieces of EU chemicals legislation, EURL ECVAM has decided to focus its efforts on the development of non-animal testing strategies for skin sensitisation hazard identification and classification, including the subcategorisation of sensitisers, according to the GHS classification system. This would satisfy the majority of the regulatory requirements within the EU and would have a significant impact in terms of replacing animal experiments. This report describes the EURL ECVAM strategy for achieving this goal.
		},
	title = {EURL ECVAM Strategy for Replacement of Animal Testing for Skin Sensitisation Hazard Identification and Classification},
	type = {Scientific analysis or review},
	url = {},
	doi = {10.2788/84255 (print),10.2788/84214 (online)}
}