Title: The Human Gut Microbiota: Overview and analysis of the current scientific knowledge and possible impact on healthcare and well-being
Authors: ANGERS ALEXANDREKAGKLI DAFNI MARIAPATAK DENNSTEDT ALEXANDREPETRILLO MAUROQUERCI MADDALENARÜDELSHEIM PATRICKSMETS GREETVAN DEN EEDE GUY
Publisher: Publications Office of the European Union
Publication Year: 2018
JRC N°: JRC112042
ISBN: 978-92-79-86471-1 (online), 978-92-79-86472-8 (print)
ISSN: 1831-9424 (online), 1018-5593 (print)
Other Identifiers: EUR 29240 EN
OP KJ-NA-29240-EN-N (online), KJ-NA-29240-EN-C (print)
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC112042
DOI: 10.2760/17381
10.2760/445187
Type: EUR - Scientific and Technical Research Reports
Abstract: Recent years have seen a fast increase in the analytical capacity to read genetic information and in the ability to understand the link between the genetic information and the functioning of organisms. This has increased the scientific knowledge in previously underexploited fields. One example is the human microbiota and the understanding of the vital role that the microbiota plays in the physiological and psychological human health status and well-being. Brain degenerative diseases like Alzheimer and Parkinson are, for example, now considered to be linked to abnormalities in the functioning of the human gut microbiota. This understanding may have revolutionary impact on (personal) healthcare but this promise has not yet been fully recognized by the general public or the policy community and for example today, microbiota-related policy interventions are mostly restricted to the marketing and health claims of possible probiotic foods and food supplements. As the JRC is holding the responsibility for the knowledge management of health-related scientific information for policy, we present and discuss here the most recent information available on the vital role of the human gut microbiota and the associated opportunities for human health and well-being. This report provides the state-of-the-art of scientific progress and details how we are only starting to learn its importance for human health, food and chemicals safety, as well as for our protection against environmental stressors. We also indicate why and how the human gut microbiota is going to have an impact on healthcare, nutrition and well-being and how this may change the way we assess the risks of the food, drugs and chemicals we are in contact with.
JRC Directorate:Health, Consumers and Reference Materials

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