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EUROCAT - Surveillance of congenital anomalies in Europe: epidemiology of Down syndrome 1990 - 2014

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Socio-economic regional microscope series
Down syndrome accounts for 8% of all congenital anomalies. It is related to maternal age, which generally increased in Europe during the study period, with large differences in European regions. The analysis of data from the JRC-EUROCAT Central registry shows that the total prevalence of Down syndrome for 10 000 births increased from 16 in 1990 to 23 in 2015. The prenatal detection increased from 49% in 2005 to about 70 % in 2015, but territorial differences between countries and regions exist.
LA PLACA Giovanni;  SPIRITO Laura; 
2019-03-18
Publications Office of the European Union
JRC115824
978-92-76-00574-2 (online),    978-92-76-00575-9 (print),   
2599-6304 (online),    2599-6290 (print),   
OP KJ-BF-19-001-EN-N (online),    OP KJ-BF-19-001-EN-C (print),   
https://publications.jrc.ec.europa.eu/repository/handle/JRC115824,   
10.2760/70796 (online),    10.2760/331810 (print),   
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