Towards FAIR Nanosafety Data

Nanotechnology is a key enabling technology with several billion Euros in global investment from public funding during the last decade, leading to large collaborative projects, which have investigated the environmental and health safety aspects of nanomaterials (NMs), but the reuse of data in safety assessment is lagging behind. Here we summarize the known challenges to the efficient reuse of nanosafety data, and how to align them with the recently established FAIR (Findable, Accessible, Interoperable, and Reusable) guiding principles. We include a set of recommendations based on experience from gathering, generating, curating and reusing nanosafety data within the European project NanoReg2. We describe the newly established Nanosafety data interface, which provides aggregated findability, accessibility and interoperability across physicochemical, bio-nano interaction, human toxicity, including omics, ecotoxicological and exposure data. In addition, a semi-quantitative evaluation of the data FAIRness is provided. This paper illustrates the path towards FAIR nanosafety data enabling maximum possible reuse of available data, to avoid duplication, plan new research and ensure safe and sustainable nanotechnology.

JELIAZKOVA Nina;  APOSTOLOVA M. D.;  ANDREOLI Cristina;  BARONE Flavia;  BARRICK Andrew;  BATTISTELLI Chiara L.;  BOSSA Cecilia;  BOTEA-PETCU Alina;  CHÂTEL Amélie;  DE ANGELIS Isabella;  DUSINSKA Maria;  EL YAMANI Naouale;  GHEORGHE Daniela;  GIUSTI Anna;  GOMEZ-FERNANDEZ Paloma;  GRAFSTRÖM R.;  GROMELSKI Maciej;  JACOBSEN Nicklas R;  JELIAZKOV V.;  ALSTRUP JENSEN Keld;  KOCHEV Nikolay;  KOHONEN Pekka;  MANIER Nocolas;  MARIUSSEN Espen;  MECH Agnieszka;  NAVAS Jose M;  PASKALEVA Vesselina;  PRECUPAS Aurelica;  PUZYN Tomasz;  RASMUSSEN Kirsten;  RITCHIE Peter;  RODRÍGUEZ LLOPIS Isabel;  RUNDÉN-PRAN Elise;  SANDU Romica;  SHANDILYA Neeraj;  TANASESCU Speranta;  HAASE Andrea;  NYMARK P.; 

2021-06-17

NATURE PUBLISHING GROUP

JRC121321

1748-3387 (online),   

https://publications.jrc.ec.europa.eu/repository/handle/JRC121321,   

10.1038/s41565-021-00911-6 (online),