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Actual cancer therapies are facing numerous challenges towards tumor cell destruction : tumor microenvironment involves immunoregulatory cells and cytokines, which prevent anti-tumoral immune response. Therapeutic combination could be the key to turn these « cold » tumor microenvironment into « hot » ones : more vascularised and infiltrated with immune cells. To this end, this project focus on combining targeted alpha-therapy (TAT) and adoptive T-cells transfer (ACT).
2020-10-15
SPRINGER
JRC121369
1619-7070 (online),   
https://publications.jrc.ec.europa.eu/repository/handle/JRC121369,   
10.1007/s00259-020-04988-4 (online),   
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