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Systematic organization of COVID-19 data supported by the Adverse Outcome Pathway framework

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Adverse Outcome Pathways (AOP) provide structured frameworks for systematic organization of research data and knowledge. The AOP framework follows a set of key principles that allow for broad application across diverse disciplines related to human health, including toxicology, pharmacology, virology and medical research. The COVID-19 pandemic engages a great number of scientists world-wide and data is increasing with exponential speed. Diligent data management strategies are employed but approaches for systematically organizing the data-derived information and knowledge are lacking. We believe AOPs can play an important role in improving interpretation and efficient application of scientific understanding of COVID-19. Here, we outline a newly initiated effort to streamline collaboration between scientists across the world towards development of AOPs for COVID-19, and describe the overarching aims of the effort, as well as the expected outcomes and research support that they will provide.
2021-05-21
FRONTIERS MEDIA SA
JRC122629
2296-2565 (online),   
https://www.frontiersin.org/articles/10.3389/fpubh.2021.638605/full,    https://publications.jrc.ec.europa.eu/repository/handle/JRC122629,   
10.3389/fpubh.2021.638605 (online),   
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