Prevalence of congenital heart defects in Europe, 2008-2015; a registry based study

The total prevalence of congenital heart defects (CHD) varies by populations and over time. The present study aimed to examine trends in the prevalence of CHD in Europe between the years 2008-2015 and to investigate if the decreasing trend reported by previous studies is continuing. It was based on high-quality population-based data derived from the large, established network of European congenital anomaly registries (EUROCAT) where both multisource case ascertainment and accurate diagnoses are achieved. Results showed that the total prevalence of CHD in Europe during the study period was 57.1 per 10,000 births. The decreasing trend reported by previous studies has not continued. However, significant differences in the total and live birth prevalence by registry were found. The study confirms the importance of regular monitoring of temporal trends in congenital anomaly prevalence, including CHDs, in Europe. This may help identify any major increases in prevalence and differences between countries/regions and identify modifiable risk factors so that this information can be used to apply relevant public health measures.

MAMASOULA Chrysovalanto;  ADDOR Marie-Claude;  CAVERO-CARBONELL Clara;  DIAS Carlos Matias;  ECHEVARRÍA-GONZÁLEZ-DE-GARIBAY Luis;  GATT Miriam;  KHOSHNOOD Babak;  KLUNGSOYR Kari;  RANDALL Kay;  STOIANOVA Sylvia;  HAEUSLER Martin;  NELEN Vera;  NEVILLE Amanda;  PERTHUS Isabelle;  PIERINI Anna;  BERTAUT-NATIVEL Benedicte;  RISSMANN Anke;  ROUGET Florence;  SCHAUB Bruno;  TUCKER David;  WELLESLEY Diana;  ZYMAK-ZAKUTNIA Natalia;  BARISIC Ingeborg;  DE WALLE Hermien;  LANZONI Monica;  MULLANEY Carmel;  PENNINGTON Lindsay;  RANKIN Judith; 

2023-01-03

WILEY

JRC130137

2472-1727 (online),   

https://onlinelibrary.wiley.com/doi/full/10.1002/bdr2.2117,    https://publications.jrc.ec.europa.eu/repository/handle/JRC130137,   

10.1002/bdr2.2117 (online),