Geographical and temporal differences in gastric and oesophageal cancer registration by subsite and morphology in Europe

Gastric and oesophageal cancers pose a serious public health concern. In 2020 a total of 189,031 incident cases (136,038 stomach, 52,993 oesophagus) and 142,508 deaths (96,997 stomach, 45,511 oesophagus) were estimated in Europe. Although incidence rates of gastric cancer have been decreasing in Europe since decades, due to ageing the burden of oesophago-gastric cancer is expected to further rise in absolute terms the in next decades, with an estimated 25% increase for gastric cancer (170,027 cases) and a 22% increase in oesophageal cancer (64,720 cases) by 2040. Oesophago-gastric cancers are a heterogeneous disease, with different aetiology and epidemiology for the various topographic subsites and main histopathological types. Topography subsite and morphology is key information to allow differentiating oesophago-gastric cancers. Correct registration and coding of such variables from population-based cancer registries is fundamental in allowing proper description of the epidemiology of different subsites and histopathological types of oesophago-gastric cancers. The objective of the paper is to highlight geographical and temporal variability in topography and morphology of oesophago-gastric cancers observed in Europe in the considered period, using data extracted from the European Cancer Information System (ECIS).

GIUSTI Francesco;  MARTOS JIMENEZ Maria Del Carmen;  BETTIO Manola;  NEGRAO DE CARVALHO Raquel;  ZORZI Manuel;  GUZZINATI Stefano;  RUGGE Massimo; 

2024-02-20

FRONTIERS MEDIA SA

JRC134072

2234-943X (online),   

https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1250107/full,    https://publications.jrc.ec.europa.eu/repository/handle/JRC134072,   

10.3389/fonc.2024.1250107 (online),