Metadata stewardship in nanosafety research: learning from the past, preparing for an “on-the-fly” FAIR future

While significant progress has been made in terms of best practice in research data management for nanosafety, some of the approaches to date are overly focussed on the needs of specific research projects or aligned to a single data repository, and this “silo” approach is hampering their general adoption by the broader research community and individual labs. The development of data capture templates has focussed on standardised single-endpoint Test Guidelines, which does not reflect the complexity of real laboratory processes where multiple assays are interlinked into an overall study, and where non-standardised assays are developed to address novel research questions and probe mechanistic processes to generate the basis for read-across from one nanomaterial to another. By focussing on the needs of data providers and data users, we identify how existing tools and approaches can be re-framed to enable “on-the-fly” (meta)data definition, data capture, curation and FAIRification, that is sufficiently flexible to address the complexity in nanosafety research, yet harmonised enough to facilitate integration of datasets from different sources generated for different research purposes.

EXNER Thomas;  PAPADIAMANTIS Anastasios;  MELAGRAKI Georgia;  AMOS Jaleesia D.;  BOSSA Nathan;  GAKIS Giorgios;  CHARITIDIS Costas A.;  CORNELIS Geert;  COSTA Anna Luisa;  DOGANIS Philip;  FARCAL Lucian;  FRIEDRICHS Steffi;  FURXHI Irini;  KLAESSIG Frederick C.;  LOBASKIN Vladimir;  MAIER Dieter;  RUMBLE John;  SARIMVEIS Haralambos;  SUAREZ-MERINO Blanca;  VÁZQUEZ-CAMPOS Socorro;  WIESNER Mark R.;  AFANTITIS Antreas;  LYNCH Iseult; 

2023-09-01

FRONTIERS MEDIA SA

JRC134764

2296-424X (online),   

https://www.frontiersin.org/articles/10.3389/fphy.2023.1233879,    https://publications.jrc.ec.europa.eu/repository/handle/JRC134764,   

10.3389/fphy.2023.1233879 (online),