Synthesis and Inhibitory Activity of 7-Geranoxycoumarin against Penicillium Species in Citrus Fruit.
A naturally occurring compound with a strong anifungal activity was isolated from flavedo tissue of 'Star Ruby' grapefruits, it was characterized and its structure elucidated. This was found to be 7-geranoxycoumarin. A high yield strategy for its synthesis was found, and its antifungal activity against Penicillium italicum and P. digitatum was gauged by tests in vivo and in vitro.
ANGIONI A.;
CABRAS P.;
D'HALLEWIN G.;
PIRISI F.M.;
RENIERO Fabiano;
SCHIRRA M.;
1997-08-11
JRC15187
https://publications.jrc.ec.europa.eu/repository/handle/JRC15187,
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