The Validation of Toxicological Prediction Models.
An alternative method consists of two parts: the test system itself, and a prediction model for converting in vitro endpoints into predictions of in vivo toxicity. It is shown that there are certain circumstances in which a new prediction model can be introduced without the necessity to generate new test systems data.
BALLS Michael;
CURREN Rodger;
FENTEM Julia Helen;
HOLZHUETTER Hermann G.;
LIEBSCH Manfred;
LOVELL David;
SOUTHEE J.A.;
1997-11-24
JRC15705
https://publications.jrc.ec.europa.eu/repository/handle/JRC15705,
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