Title: The Validation of Toxicological Prediction Models.
Authors: BALLS MichaelCURREN RodgerFENTEM Julia helenHOLZHUETTER Hermann, g.LIEBSCH ManfredLOVELL DavidSOUTHEE J.a.
Citation: Alternatives to Laboratory Animals vol. 25 p. 505-515
Publication Year: 1997
JRC N°: JRC15705
URI: http://publications.jrc.ec.europa.eu/repository/handle/JRC15705
Type: Articles in periodicals and books
Abstract: An alternative method consists of two parts: the test system itself, and a prediction model for converting in vitro endpoints into predictions of in vivo toxicity. It is shown that there are certain circumstances in which a new prediction model can be introduced without the necessity to generate new test systems data.
JRC Directorate:Joint Research Centre Historical Collection

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