Reducing the Use of Laboratory Animals in Biomedical Research: Problems and Possibke Solutions.

Abstract

4 MCR Toxicology Unit, University of Leicester, Lancaster road, Leicester LE1 9HN, UK; 5 Department of Laboratory Animal Science University of Utrecht, 3508 TD Utrecht, The Netherlands; 6 FRAME, Russell & Burch House, 96-98 North Sherwood Street, Nottingham NG1 4EE, UK; 7 ECVAM, JRC Environment Institute, 21020 Ispra (VA), Italy; 8 National Institute of Public Health and Environment, 3720 BA Bilthoven, The Netherlands; 9 Field Laboratories, Medical School, University of Sheffield, Beach Hill Road, Sheffield S10 2RX, UK; 10 BIBRA International, Woodmansterne Road, Carshalton, Surrey SM5 4DS, UK: 11 Pfizer Central Research, Sandwich, Kent CT13 9NJ, UK : 12 SmithKline Beecham Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex CM19 5AW,UK: 13 Merck Sharp & Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Harlow, Essex CM20 2QR, UK.