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|Title:||Cytotoxicity of PAI2, C595 and Herceptin Vectors Labeled with the Alpha-Emitting Radioisotope Bismuth-213 for Ovarian Cancer Cell Monolayers and Clusters|
|Authors:||SONG Y.j.; QU C.f.; RIZVI S.m.a.; LI Y.; ROBERTSON G.; RAJA C.; MORGENSTERN ALFRED; APOSTOLIDIS CHRISTOS; PERKINS A.c.; ALLEN Barry J.|
|Citation:||CANCER LETTERS vol. 234 p. 176-183|
|Publisher:||ELSEVIER SCI LTD|
|Type:||Articles in periodicals and books|
|Abstract:||The vectors PAI2, C595 and Herceptin target the membrane-bound uPA, MUCl and HER2 antigens expressed by cancer cells, respectively. The expression of these receptors was tested in the ovarian cancer cell line OVCAR-3; MUC-I was strongly expressed (3 -|->, uPA moderately expressed (2+), but HER2 was negatíve|
|JRC Directorate:||Nuclear Safety and Security|
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