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http://publications.jrc.ec.europa.eu/repository/handle/JRC33606
Title: | Pre-clinical Study of 213Bi Labeled PAI2 for the Control of Micrometastatic Pancreatic Cancer |
Authors: | QU C.f.; SONG E.; LI Y.; RIZVI S.m.a.; RAJA C.; ROSS R; APOSTOLIDIS CHRISTOS; ALLEN Barry J. |
Editors: | MORGENSTERN ALFRED |
Citation: | CLINICAL & EXPERIMENTAL METASTASIS vol. 22 p. 575-586 |
Publisher: | SPRINGER |
Publication Year: | 2005 |
JRC N°: | JRC33606 |
URI: | http://publications.jrc.ec.europa.eu/repository/handle/JRC33606 |
Type: | Articles in periodicals and books |
Abstract: | Purpose: The urokinase plasminogen activator (uPA) and its receptor (uPAR) are expressed by pancreatic cancer cells and can be targeted by the plasminogen activator inhibitor type 2 (PAI2). We have labeled PAI2 with 213Bi to form the alpha conjugate (AC), and have studied its in vitro cytotoxicity and in vivo efficacy. |
JRC Directorate: | Nuclear Safety and Security |
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