Formation of Viscoelastic Protein Droplets on a Chemically Functionalized Surface
Droplet formation during adsorption of the protein lactoferrin from an aqueous solution on a surface functionalized by plasma deposited poly(acrylic acid) is studied using quartz crystal microbalance and atomic force microscopy. The formation of protein droplets is particularly favored at pH values close to the isoelectric point of lactoferrin, where the molecules carry little excess charge and intermolecular attraction exceeds the molecule-surface interaction. By combining topographic data with information on the system dynamics it is possible to describe the viscoelastic properties of the adsorbate within a quantitative model for non-homogeneous layers.
BELEGRINOU S.;
MANNELLI Ilaria;
SIRGHI Lucel;
BRETAGNOL Frederic;
VALSESIA Andrea;
RAUSCHER Hubert;
ROSSI Francois;
2008-02-19
AMER CHEMICAL SOC
JRC42188
1520-6106,
https://publications.jrc.ec.europa.eu/repository/handle/JRC42188,
10.1021/jp073297x,
Additional supporting files
| File name | Description | File type | |
|---|
