Use of Nanopatterned Surfaces To Enhance Immunoreaction Efficiency
In this work, we compare the immunoreaction efficiency between uniformly functionalized surface and chemically nanopatterned surfaces when applied as platforms for antigen/antibody interactions with and without the use of protein A as orienting protein. On the anopatterned platform, the immunoreaction efficiency is higher than all the other cases with no protein A pretreatment of the
surface, providing evidence of the capability of the adhesive/antiadhesive nanopatterned surface to immobilize the molecules in a reactive state, increasing their possibility to form complexes.
VALSESIA Andrea;
COLPO Pascal;
MANNELLI Ilaria;
MORNET Stephane;
BRETAGNOL Frederic;
CECCONE Giacomo;
ROSSI Francois;
2008-03-05
AMER CHEMICAL SOC
JRC43109
0003-2700,
https://publications.jrc.ec.europa.eu/repository/handle/JRC43109,
10.1021/ac701762k,
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