Selective Elimination of Synovial Macrophages by Boron Neutron Capture Therapy Prevents Onset of Murine Experimental Arthritis

VAN, LENT Peter; SLOETJES, Annet; BLOM, Arjen; KRIJGER, Gerard C.; KONING, Gerben A.; NIEVAART, Victor Alexander; VAN, DEN BERG Wim; MOSS, Raymond

doi:10.1016/j.jconrel.2006.09.073

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Selective Elimination of Synovial Macrophages by Boron Neutron Capture Therapy Prevents Onset of Murine Experimental Arthritis

Selective delivery of boron-10 encapsulated in liposomes to synovial macrophages in knee joints of mice combined with neutron irradiation (boron neutron capture therapy: BNCT) almost completely prevents the onset of experimental arthritis.

VAN LENT Peter; SLOETJES Annet; BLOM Arjen; KRIJGER Gerard C.; KONING Gerben A.; NIEVAART Victor Alexander; VAN DEN BERG Wim; MOSS Raymond;

2008-10-23

ELSEVIER SCIENCE BV

JRC45878

0168-3659,

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T3D-4MH9SS7-23&_user=4692146&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000036252&_version=1&_urlVersion=0&_userid=4692146&md5=7dc779a0a68cc23fdcf577f102a3827b, https://publications.jrc.ec.europa.eu/repository/handle/JRC45878,

10.1016/j.jconrel.2006.09.073,

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