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http://publications.jrc.ec.europa.eu/repository/handle/JRC48528| Title: | Radiofungicidal Effects of External Gamma Radiation and Antibody-Targeted Beta and Alpha Radiation on Cryptococcus neoformans |
| Authors: | BRYAN R. A.; MORGENSTERN Alfred; BRUCHERTSEIFER Frank; CASADEVALL A.; DADACHOVA E. |
| Citation: | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY vol. 52 no. 6 p. 2232-2235 |
| Publisher: | AMER SOC MICROBIOLOGY |
| Publication Year: | 2008 |
| JRC N°: | JRC48528 |
| ISSN: | 0066-4804 |
| URI: | http://aac.asm.org/ http://publications.jrc.ec.europa.eu/repository/handle/JRC48528 |
| DOI: | 10.1128/AAC.01245-07 |
| Type: | Articles in periodicals and books |
| Abstract: | We evaluated the clonogenic survival, membrane permeability, metabolic activity (XTT reduction), and apoptosis (FLICA binding) of Cryptococcus neoformans cells subjected to gamma rays from an external source, and beta and alpha particles delivered to fungal cells by capsule-specific antibody. We found that gamma, beta, and alpha radiation affected cells through different pathways. |
| JRC Directorate: | Nuclear Safety and Security |
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