HRGC-HRMS Multi-Residual POPs Analysis Method On A Novel Automated Clean Up System

Persistent Organic Pollutants (POPs) are toxic, persistent and lipophilic chemicals. A multi-residual method for 29 organochlorinated pesticides (OCPs), indicator and dioxin-like polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) in fish has been developed analyzing reference material on a novel automated clean up system. Through in line gel permeation chromatography, acid silica/neutral silica, basic alumina and active carbon columns clean up steps the method provides distinct fractions for multiple run HRGC-HRMS analysis. The recovery of labelled internal standards was in the range indicated by the official methods. The results were in good agreement with reference values. The automated system is equipped with an autosampler and runs in sequential mode up to 9 samples. The method fits the purpose of multi-residual methods.

MARIANI Giulio;  AMALFITANO Lara;  MANNI Andrea;  MUELLER Anne;  SKEJO Helle;  UMLAUF Gunther; 

2009-10-07

Prof. Guibin Jiang

JRC52940