Measurement of excitation functions for production of cerium radioisotopes by deuteron induced reactions on natural cerium for nanobioscience applications

Cerium based nanoparticles would play an important role in the field of nanotechnology ranging from fuel additives to sun creams, and to various medical applications. Radiolabelled cerium can be accurately and precisely traced during each step of their applications, thanks to the sensitivity of nuclear measurement techniques. This work is focused on the study of the production of cerium radioisotopes and more precisely, as few data are available, on the determination of the excitation functions for production of cerium radioisotopes by deuteron induced nuclear reactions on natural cerium. We measured the excitation functions for the nuclear reactions natCe(d,x)139g,141,143Ce and also for natCe(d,x)142gPr in the energy range of 5 to 19.5 MeV. Theoretical simulations of these excitation functions were performed using the TALYS calculation code. We have shown that with deuteron beam irradiation, several radioisotopes of cerium can be activated and the cross section data of the relevant nuclear reactions are produced for the first time. Thick target yields of 0.1, 1.1 and 3.2 MBq/¿A.h were reached for 139gCe, 141Ce and 143Ce, respectively, which are sufficient for various biological studies such as cellular uptake of cerium based nanoparticles.

SIMONELLI Federica;  ABBAS Kamel;  CHAU HUU-TAI P;  HOLZWARTH Uwe;  CYDZIK Izabela; 

2010-05-04

OLDENBOURG VERLAG

JRC56356

0033-8230,   

https://publications.jrc.ec.europa.eu/repository/handle/JRC56356,   

10.1524/ract.2010.1709,